Claudin-18 Antibody (IHC)

Claudin-18 is a tight-binding protein encoded by the human CLDN18 gene and a member of the Claudins family. Claudin-18 is specifically expressed in lung and gastric tissues, with complete membrane localization on lung and gastric epithelial cells, and electron microscopy shows that it is mainly concentrated at the cell-cell boundaries of these cells. These characteristics suggest that Claudin-18 has a potentially important role in the structure and function of tight junctions in the lungs and stomach.