CD13 Antibody (IHC)

CD13 is a transmembrane protease found in multiple tissue cell types such as endothelial cells, epithelial cells, fibroblasts, and granulocytes. The high expression of CD13 in tumor cells makes it very useful in the diagnosis of subtypes of AML, but it needs to form a series with CD34(+), CD117(+), CD16(-) and CD33(+) for diagnosis. The high expression of CD13 in myeloid sarcoma makes it very useful in the diagnosis of this tumor as well. CD13 is expressed in normal livers and tumors, and its distribution pattern is similar to that of multi-anti-CEA and CD10 in a tubule-like pattern. Therefore CD13 can be used as a marker to differentiate hepatocellular carcinoma from non-hepatocellular carcinoma.