PTEN Antibody (IHC)

PTEN (phosphatase and tensin homologue deleted from chromosome 10), also known as MMAC1 or TEP1, is located on human chromosome 10q23. It is a tumor suppressor gene that encodes a multifunctional phosphatase that is widely expressed in maintaining cell proliferation, differentiation, Apoptosis plays an important role. This gene shows loss of heterozygosity or mutation in many tumors and is mainly used in the research of breast cancer, malignant melanoma, endometrial cancer, bladder cancer, lung small cell carcinoma, and ovarian endometrioid cancer.