c-KIT/CD117 Antibody (IHC)

C-kit is the protein product of the proto-oncogene and is a type III transmembrane protein tyrosine kinase growth factor receptor protein. 80-100% gastric stromal sarcoma (GIST) CD117+, can be combined with CD34. CD117 can also be used to identify mast cell tumors in lymphoma and as a marker for some testicular germ cell tumors. Recent studies have shown that CD117, as a specific immunohistochemical marker for gastric stromal sarcoma (GIST), can be used to clinically guide personalized target drug (Gleevec) treatment for GIST patients.