ERCC1 Antibody (IHC)

ERCC1 is a highly conserved excisional ribozyme in the nucleotide excision repair pathway and is necessary for efficient repair of DNA complexes induced by alkylating agents. Current research data shows that if ERCC1 protein expression is negative, patients may gain survival benefit from adjuvant cisplatin chemotherapy; ERCC1 protein expression may indicate resistance to platinum drugs, and ERCC1 protein expression may become one of the indicators of whether patients should receive cisplatin adjuvant chemotherapy. one.