Synaptophysin Antibody (IHC)

Synaptophysin is a glycoprotein that exists in the preneuronal vesicle membrane and is one of the specific markers of neuroendocrine tumors. It is mainly expressed in the presynaptic membrane of neurons and the adrenal medulla, carotid bodies, skin, In neuroendocrine cells and tumors of the pituitary gland, thyroid, lung, pancreas and gastrointestinal mucosa. It is mainly used for the diagnosis and differential diagnosis of pheochromocytoma, ganglioneuroma, paraganglioma and APUD system tumors.